ZHANG, YONG,BORZILLERI, ROBERT M.,TEBBEN, ANDREW J.,STANG, ERIK M.,DONNELL, ANDREW F.,SCHROEDER, GRETCHEN M.,PEREZ, HEIDI L.,WEI, DONNA D.
申请号：
CA2990030
公开号：
CA2990030A1
申请日:
2016.06.22
申请国别(地区):
CA
年份:
2016
代理人:
摘要：
Macrocyclic benzodiazepine dimers having a structure represented by formula (I) where A and B are independently according to formulae (Ia) or (Ib) ]； and the other variables in formulae (I), (Ia), and (Ib) are as defined in the application. Such dimers are useful as anti-cancer agents, especially when used as the drug component in an antibody-drug conjugate (ADC).
