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COMBINATION OF ANTI-CANCER AGENTS
专利权人:
СПЕКТРУМ ФАРМАСЬЮТИКАЛЗ; ИНК. (US)
发明人:
РЕДДИ Гуру (US),ЛЕНАЗ Луиджи (US)
申请号:
RU2010139840/15
公开号:
RU2010139840A
申请日:
2009.02.20
申请国别(地区):
RU
年份:
2012
代理人:
摘要:
1. A method for treating cancer in a mammal, comprising:! administration of lucanton to a mammal; and! administration of at least one antimetabolite to a mammal,! wherein said lucanton and said at least one antimetabolite are administered in therapeutically effective amounts. ! 2. The method according to claim 1, where the specified at least one antimetabolite is a folate antimetabolite. ! 3. The method according to claim 1, where the specified at least one antimetabolite is pemetrexed (Pemetrexed). ! 4. The method according to claim 1, where the specified lucanton and the specified at least one antimetabolite are administered simultaneously. ! 5. The method according to claim 1, where the specified lucanton and the specified at least one antimetabolite are administered sequentially. ! 6. The method according to claim 5, where each of the specified lucanton and the specified at least one antimetabolite are administered within about three hours. ! 7. The method according to claim 5, where each of the specified lucanton and the specified at least one antimetabolite are administered within about two hours. ! 8. The method according to claim 5, where each of the specified lucanton and the specified at least one antimetabolite are administered within about one hour. ! 9. The method of claim 1, wherein said cancer is lung cancer. ! 10. The method according to claim 9, where the specified lung cancer is a non-small cell lung carcinoma. ! 11. The method according to claim 1, wherein said therapeutically effective amount of lucanton and said therapeutically effective amount of at least one antimetabolite are administered in a single daily dose or divided into more than one daily dose. ! 12. The method according to claim 11, where the specified more than one day�1. Способ лечения рака у млекопитающего, включающий: ! введение люкантона млекопитающему; и ! введение, по меньшей мере, одного антиметаболита млекопитающему, ! где указанный люкантон и указанный, по меньшей мере,
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