Harald Arno Butterweck,Bernhard Kölbl,Lucia Gnauer,Wolfgang Teschner,Hans-Peter Schwarz
申请号：
US15859108
公开号：
US20180250401A1
申请日:
2017.12.29
申请国别(地区):
US
年份:
2018
代理人:
摘要：
The present invention provides, among other aspects, storage stable aqueous formulations of immunoglobulins with histidine at a mildly acidic to neutral pH. The present invention also provides methods for stabilizing immunoglobulin compositions by formulating with histidine at a mildly acidic to neutral pH. Advantageously, the methods and formulations provided herein allow stable aqueous compositions of immunoglobulins at mildly acidic to neutral pH useful for parenteral administration.
