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Stabilization of immunoglobulins through aqueous formulation with histidine at weak acidic to neutral pH
专利权人:
Baxter International Inc.;Baxter Healthcare S.A.
发明人:
Butterweck, Harald Arno,Kolbl, Bernhard,Hofbauer, Lucia,Teschner, Wolfgang,Schwarz, Hans-Peter
申请号:
AU2011301807
公开号:
AU2011301807A1
申请日:
2011.09.16
申请国别(地区):
AU
年份:
2013
代理人:
摘要:
The present invention provides, among other aspects, storage stabile aqueous formulations of immunoglobulins with histidine at a mildly acidic to neutral pH. The present invention also provides methods for stabilizing immunoglobulin compositions by formulating with histidine at a mildly acidic to neutral pH. Advantageously, the methods and formulations provided herein allow stabile aqueous compositions of immunoglobulins at mildly acidic to neutral pH useful for parenteral administration.
来源网站:
中国工程科技知识中心
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http://www.ckcest.cn/home/

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