Butterweck, Harald Arno,Kolbl, Bernhard,Hofbauer, Lucia,Teschner, Wolfgang,Schwarz, Hans-Peter
申请号:
AU2011301807
公开号:
AU2011301807A1
申请日:
2011.09.16
申请国别(地区):
AU
年份:
2013
代理人:
摘要:
The present invention provides, among other aspects, storage stabile aqueous formulations of immunoglobulins with histidine at a mildly acidic to neutral pH. The present invention also provides methods for stabilizing immunoglobulin compositions by formulating with histidine at a mildly acidic to neutral pH. Advantageously, the methods and formulations provided herein allow stabile aqueous compositions of immunoglobulins at mildly acidic to neutral pH useful for parenteral administration.