Harald Arno Butterweck,Bernhard Kölbl,Lucia Hofbauer,Wolfgang Teschner,Hans-Peter Schwarz
申请号：
US14311112
公开号：
US09855331B2
申请日:
2014.06.20
申请国别(地区):
US
年份:
2018
代理人:
摘要：
The present invention provides, among other aspects, storage stabile aqueous formulations of immunoglobulins with histidine at a mildly acidic to neutral pH. The present invention also provides methods for stabilizing immunoglobulin compositions by formulating with histidine at a mildly acidic to neutral pH. Advantageously, the methods and formulations provided herein allow stabile aqueous compositions of immunoglobulins at mildly acidic to neutral pH useful for parenteral administration.
