STABILIZATION OF IMMUNOGLOBULINS THROUGH AQUEOUS FORMULATION WITH HISTIDINE AT WEAK ACIDIC TO NEUTRAL PH

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专利权人:

BAXTER INTERNATIONAL INC.

发明人:

BUTTERWECK, HARALD, ARNO,KÖLBL, BERNHARD,HOFBAUER, LUCIA,TESCHNER, WOLFGANG,SCHWARZ, HANS-PETER

申请号：

SG2013017728

公开号：

SG188487A1

申请日:

2011.09.16

申请国别(地区):

SG

年份:

2013

代理人:

摘要：

The present invention provides, among other aspects, storage stabile aqueous formulations of immunoglobulins with histidine at a mildly acidic to neutral pH. The present invention also provides methods for stabilizing immunoglobulin compositions by formulating with histidine at a mildly acidic to neutral pH. Advantageously, the methods and formulations provided herein allow stabile aqueous compositions of immunoglobulins at mildly acidic to neutral pH useful for parenteral administration.

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/