BUTTERWECK, HARALD ARNO,KOLBL, BERNHARD,HOFBAUER, LUCIA,TESCHNER, WOLFGANG,SCHWARZ, HANS-PETER
申请号:
CA2810734
公开号:
CA2810734A1
申请日:
2011.09.16
申请国别(地区):
CA
年份:
2012
代理人:
摘要:
The present invention provides, among other aspects, storage stabile aqueous formulations of immunoglobulins with histidine at a mildly acidic to neutral pH. The present invention also provides methods for stabilizing immunoglobulin compositions by formulating with histidine at a mildly acidic to neutral pH. Advantageously, the methods and formulations provided herein allow stabile aqueous compositions of immunoglobulins at mildly acidic to neutral pH useful for parenteral administration.