The way to achieve ontology refers to therapeutic compounds of alternative heterocyclic derivatives, including their components, and the use of these compounds and components to regulate congenitality by inhibiting intermediate P recognition. O Bromine domains of acetic acid-containing protein regions, such as tissues. These ingredients and methods help to treat diseases caused by abnormal cellular signals, such as inflammation.Cancer and New Shaping Diseases Compared with BrD4, the specific compounds described in this report have selective inhibitory activities against CBP. Claim 1: Compounds with a formula structure (1),1. A prescription compound (1) contains a salt acceptable to the drug, and X8310N or CR8311A are positive；R831181 is hydrogen, halogen, tar or alcoxi； R2 is hydrogen, tar, Arilo, Aralquilo, cycloquilo, cycloquilo, cycloquilo, isopropylene, isopropylene or isopropylene； R83099 is hydrogen, halogen, -CN-N (square kilometer) 832222；- NH(r2),- N(r2) SO8322； R 2,- N (r2) So8322； N (r2) 832222；- N(r2)Co(r2),- N(r2) CO8322； R 2,- N (r2) con (r2) 832222；- OC (O) N (R 2) 832222；- C (O) N (R square) 832222；- Ow, NW, SW, SO83222； W, or tar, Arilo, Aralquilo, straight, straight, straight, straight, ring, ring carat, heterocyclic or heterocyclic, alternative, W is at least one kind of hydrogen, -N (square kilometer) 832222；O Tar, Arilo, Aralquilo, cycloquilo, cycloquilo, cycloquilo, isomerization, isomerization, isomerization or isomerization substitutes； R8310e is hydrogen, halogen, -CN, tar, cycloquilo, cycloquilo, cycloquilo, cyclokralquilo, Arilo, Aralquilo, isomerization, isomerization or isomerization； - Abnormity-O-N (square kilometer) 832222；O R83099 and R8310A are combined to form a ring consisting of 5 to 6 optional replacement members； RA is an optional irregular substitute with N in it； among them, hydrogen, tar, cyclomethalene, cyclomethaquilo, Arilo, Aralquilo and isopropylene are independently selected per square kilometer. Abnormity, abnormity,
