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Substituted Aromatic Sulfur Compounds and Methods for their use in the treatment and Prevention of cancer
专利权人:
CEPHALON, INC.;UNIVERSITY OF HAWAII;UNIVERSITY OF UTAH RESEARCH FOUNDATION
发明人:
DORSEY BRUCE,THEROFF JAY P.,KUWADA SCOTT K.,ZIFICSAK CRAIG A.
申请号:
ARP120100605
公开号:
AR085392A1
申请日:
2012.02.23
申请国别(地区):
AR
年份:
2013
代理人:
摘要:
Add formula compound (1) and method (1): formula compound (1) used to treat or reduce the cancer risk of peritonitis,Or a pharmaceutically acceptable form of salt water, where D is a formula compound (2),(3)(4)(5) (6)N is 0, 1 or 2; RA is hydrogen, tar or phenyl; Rb is hydrogen, cyanogen, tar, phenyl, amino or oxycarbide; RC is hydrogen, cyanogen, tar, phenyl, amino or oxycarbide; A1 and A2 are independent hydrogen, or the rest of a group of products (7),Where q is o or s, R1 and R2 are replaced or not replaced tar, or R1 and R2, respectively, and the carbon atoms connected with them form a replaced or not replaced cyclopentane ring composed of 3 to 7 members, or R1 and R2, plus the carbon protons connected with them, A group consisting of alternative or unsubstituted tar, alternative or unsubstituted ring electrolysis, alternative or unsubstituted ring electrolysis, alternative or unsubstituted epoxy, alternative or unsubstituted arilo, alternative or unsubstituted spirit,Non positive molecular substitution or non substitution. Alternative or unsubstituted tequila; o-nr4r5; R4 and R5 are: independent h, alternative or unsubstituted, alternative or unsubstituted, alternative or unsubstituted asphalt, alternative or unsubstituted oxidized asphalt, alternative or unsubstituted cyclopentanediol, Substituted or unsubstituted allylic compounds, substituted or unsubstituted arilo, substituted or unsubstituted aralquilo, substituted or unsubstituted allylic, substituted or unsubstituted allylic, substituted or unsubstituted allylic, substituted or unsubstituted allylic, substituted or unsubstitutedTogether with the atoms connected together, they form a substituted or unsubstituted isopropyl ring; R6 is the substituted or unsubstituted tar, the substituted or unsubstituted arilo, the substituted or unsubstituted alien, the substituted or unsubstituted aralqui, or the substituted or unsubstituted isopropyl. RD is substituted or unsubstituted tar, substituted or unsubstituted
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