LÜCKING, Ulrich,BÖHNKE, Niels,SCHOLZ, Arne,LIENAU, Philip,SIEMEISTER, Gerhard,BÖMER, Ulf,KOSEMUND, Dirk,BOHLMANN, Rolf,ZORN, Ludwig
申请号：
ES13782670
公开号：
ES2595222T3
申请日:
2013.10.15
申请国别(地区):
ES
年份:
2016
代理人:
摘要：
A compound of the general formula (I) ** Formula ** in which R 1 represents a group selected from C 1 -C 6 alkyl, C 3 -C 7 cycloalkyl, heterocyclyl, phenyl, heteroaryl, C 1 -C 3 alkyl or heteroaryl alkyl C1-C3-, wherein said group is optionally substituted with one or two or three substituents, identically or differently, selected from the group of hydroxy, cyano, halogen, halo-C1-C3 alkyl-, C1-C6 alkoxy -, C1-C3 fluoroalkoxy-, -NH2, alkylamino-, dialkylamino-, acetylamino-, N-methyl-N-acetylamino-, cyclic amines； -OP (O) (OH) 2, -C (O) OH, -C (O) NH2； R2 represents a group selected from ** Formula ** R3, R4 independently represent each other, a group selected from a hydrogen atom, fluorine atom, chlorine atom, bromine atom, cyano, C1-C3- alkyl, alkoxy C1-C3-, halo-C1-C3- alkyl, C1-C3 fluoroalkoxy； R5 represents a group selected from a) a C1-C6 alkyl group, which is optionally substituted with one or two or three substituents, identically or differently, selected from halogen, hydroxy, -NH2, alkylamino-, dialkylamino-, acetylamino- , Nmethyl- N-acetylamino-, cyclic amines, cyano, C1-C3 alkyl-, halo-C1-C3 alkyl-, C1-C3 fluoroalkoxy-, C1-C3- alkoxy, C2-C3 alkenyl, C2-C3 alkynyl- , C3-C7- cycloalkyl, heterocyclyl-, phenyl, heteroaryl, wherein said C3-C7- cycloalkyl-, heterocyclyl-, phenyl or heteroaryl group is optionally substituted with one, two or three substituents, identically or differently, selected from halogen, hydroxy, C1-C3 alkyl-, C1-C3- alkoxy, -NH2, alkylamino-, dialkylamino-, acetylamino-, N-methyl-N-acetylamino-, cyclic amines, C1-C3 haloalkyl- C1-C3 fluoroalkoxy -； b) a C3-C7- cycloalkyl group, which is optionally substituted with one or two or three substituents, identically or differently, selected from the group of halogen, hydroxy, -NH2, alkylamino-, dialkylamino-, acetylamino-, N -methyl-N-acetylamino-, cyclic amines, cyano, C1-C3 alkyl-, halo-C1-C3 alkyl-, C1-C3 fluoroalkoxy-, C1-C3 alkoxy-, C2-C3 alkenyl, C2-C3 alkynyl- ； c) a heterocyclyl- grou
