LÜCKING, Ulrich,BÖHNKE, Niels,SCHOLZ, Arne,LIENAU, Philip,SIEMEISTER, Gerhard,BÖMER, Ulf,KOSEMUND, Dirk,BOHLMANN, Rolf,ZORN, Ludwig
申请号：
ES13777070
公开号：
ES2616441T3
申请日:
2013.10.16
申请国别(地区):
ES
年份:
2017
代理人:
摘要：
A compound of general formula (I) ** Formula ** in which R 1 represents a group selected from C 1 -C 6 alkyl, C 3 -C 7 cycloalkyl, heterocyclyl, phenyl, heteroaryl, C 1 -C 3 alkyl or heteroaryl-C1-C3-alkyl, wherein said group is optionally substituted with one or two or three identical or different substituents, selected from the group of hydroxy, cyano, halogen, halo-C1-C3- alkyl, alkoxy -C1-C6-, fluoroalkoxy-C1-C3-, - NH2, alkylamino-, dialkylamino-, acetylamino-, N-methyl-N-acetylamino-, cyclic amines, -OP (O) (OH) 2, -C ( O) OH, - C (O) NH2； R2 represents a group selected from ** Formula ** R3, R4 represents, independently of each other, a group selected from a hydrogen atom, fluorine atom, chlorine atom, bromine atom, cyano, C1-C3 alkyl -, C1-C3- alkoxy, halo-C1-C3- alkyl, fluoroalkoxy-C1-C3-； R5 represents a group selected from a) a C1-C6 alkyl group, which is optionally substituted with one or two or three identical or different substituents, selected from halogen, hydroxy, -NH2, alkylamino-, dialkylamino-, acetylamino-, N-methyl-N20 acetylamino-, cyclic amines, cyano, C1-C3- alkyl, halo-C1-C3- alkyl, fluoroalkoxy-C1-C3-, C1-C3 alkoxy-, alkenyl-C2-C3-, alkynyl-C2-C3-, cycloalkyl-C3-C7-, heterocyclyl-, phenyl, heteroaryl, wherein said cycloalkyl-C3-C7-, heterocyclyl-, phenyl or heteroaryl group is optionally substituted with one, two or three substituents, identical or different, selected from halogen, hydroxy, alkyl-C1-C3-, alkoxy-C1-C3-, -NH2, alkylamino-, dialkylamino-, acetylamino-, N-methyl-N-acetylamino-, cyclic amines, halo- C1-C3- alkyl, fluoroalkoxy-C1-C3-； b) a cycloalkyl-C3-C7- group, which is optionally substituted with one or two or three identical or different substituents, selected from the group of halogen, hydroxy, -NH2, alkylamino-, dialkylamino-, acetylamino-, N- methyl-N-acetylamino-, cyclic amines, cyano, C1-C3 alkyl-, halo-C1-C3- alkyl, fluoroalkoxy-C1- C3-, alkoxy-C1-C3-, alkenyl-C2-C3-, alkynyl -C2-C3-； c) a heterocyclyl- group, which i
