ADAMS, NICHOLAS D,BURGESS, JOELLE LORRAINE,DARCY, MICHAEL GERARD,DONATELLI, CARLA A,KNIGHT, STEVEN DAVID,NEWLANDER, KENNETH ALLEN,RIDGERS, LANCE,SARPONG, MARTHA,SCHMIDT, STANLEY J.
申请号：
ES13156120
公开号：
ES2547256T3
申请日:
2008.05.16
申请国别(地区):
ES
年份:
2015
代理人:
摘要：
A compound of Formula (I): ** Formula ** wherein R2 is a substituted pyridinyl or pyridinyl group, R1 is selected from a group consisting of: heterocycloalkyl, substituted heterocycloalkyl, aryl, substituted aryl, heteroaryl and substituted heteroaryl； each R3 is independently selected from: hydrogen, halogen, acyl, amino, substituted amino, C1-C6 alkyl, substituted C1-C6 alkyl, C3-C7 cycloalkyl, substituted C3-C7 cycloalkyl, C3-C7 heterocycloalkyl, substituted C3-C7 heterocycloalkyl , alkylcarboxy, aminoalkyl, aryl, substituted aryl, heteroaryl, substituted heteroaryl, arylalkyl, substituted arylalkyl, arylcycloalkyl, substituted arylcycloalkyl, heteroarylalkyl, substituted heteroarylalkyl, cyano, hydroxyl, alkoxy, nitro, acyloxy； and R4 is independently selected from: hydrogen, halogen, acyl, amino, substituted amino, C1-C6 alkyl, substituted C1-C6 alkyl, C3-C7 cycloalkyl, substituted C3-C7 cycloalkyl, C3-C7 heterocycloalkyl, substituted C3-C7 heterocycloalkyl , alkylcarboxy, aminoalkyl, aryl, heteroaryl, substituted heteroaryl, arylalkyl, substituted arylalkyl, arylcycloalkyl, substituted arylcycloalkyl, heteroarylalkyl, substituted heteroarylalkyl, cyano, hydroxyl, alkoxy, nitro, acyloxy and aryloxy； and n is 1-2； or a pharmaceutically acceptable salt thereof.Un compuesto de Fórmula (I): **Fórmula** en la que R2 es un grupo piridinilo o piridinilo sustituido, R1 está seleccionado de un grupo que consiste en: heterocicloalquilo, heterocicloalquilo sustituido, arilo, arilo sustituido, heteroarilo y heteroarilo sustituido； cada R3 está seleccionado independientemente de: hidrógeno, halógeno, acilo, amino, amino sustituido, alquilo C1-C6, alquilo C1-C6 sustituido, cicloalquilo C3-C7, cicloalquilo C3-C7 sustituido, heterocicloalquilo C3-C7, heterocicloalquilo C3-C7 sustituido, alquilcarboxi, aminoalquilo, arilo, arilo sustituido, heteroarilo, heteroarilo sustituido, arilalquilo, arilalquilo sustituido, arilcicloalquilo, arilcicloalquilo sustituido, heteroarilalquilo,
