Papayannopoulou, Thalia;Bonig, Halvard B.;Hudecek, Michael
发明人:
Papayannopoulou, Thalia,Bonig, Halvard B.,Hudecek, Michael
申请号：
EP18741084
公开号：
EP3570850A4
申请日:
2018.01.18
申请国别(地区):
EP
年份:
2020
代理人:
摘要：
Described herein are methods of promoting engraftment of a cell transplant and methods of killing hematopoietic stem cells by administering a population of T cells, NK cells or cytotoxic immune effector cells comprising a cell-surface receptor for a stem cell-specific antigen. Also described herein is a composition comprising T cells, NK cells or cytotoxic immune effector cells genetically modified to encode a cell-surface receptor for a stem cell-specific antigen.
