Pengfei Zhou,Tao Wang,Liu Hu,Mi Huang,Lijuan Fang,Yang Liu
申请号：
US15327973
公开号：
US20180312606A1
申请日:
2014.07.21
申请国别(地区):
US
年份:
2018
代理人:
摘要：
Provided are compositions comprising a MSBODY and a cytotoxic immune cell (e.g., Cytokine-induced killer cell) to form Armed Activated CIK cells (ACCs), wherein the MSBODY comprising a first antigen binding moiety that has specificity for a tumor antigen, and a second antigen binding moiety that binds to the cell. Provided are also methods preparing a composition comprising a MSBODY and a cytotoxic immune cell, and methods for treating patients with CIK cells armed with bispecific antibodies.
