Thalia PAPAYANNOPOULOU;Halvard B. BONIG;Michael HUDECEK
发明人:
Thalia PAPAYANNOPOULOU,Halvard B. BONIG,Michael HUDECEK
申请号：
US16478995
公开号：
US20190350980A1
申请日:
2018.01.18
申请国别(地区):
US
年份:
2019
代理人:
摘要：
Described herein are methods of promoting engraftment of a cell transplant and methods of killing hematopoietic stem cells by administering a population of T cells, NK cells or cytotoxic immune effector cells comprising a cell-surface receptor for a stem cell-specific antigen. Also described herein is a composition comprising T cells, NK cells or cytotoxic immune effector cells genetically modified to encode a cell-surface receptor for a stem cell-specific antigen.
