Identify that anti-myostatin antibodies, characteristic have high-affinity, Bing and the immunoconjugate or its antigen-binding fragment that can be chimeric antibody, humanized antibody or fully human antibodies, antibody in what. Antibody what of the invention increases muscle quality in mammal and avian species, increases bone density or treats a variety of diseases with what.鑒定抗肌抑制素抗體,其特徵在於具有高親和力,幷且可以是嵌合抗體、人源化抗體或完全人抗體、抗體的免疫交聯物或其抗原結合片段。本發明的抗體用於在哺乳動物和禽類物種中增加肌肉質量、增加骨密度或用於治療多種疾病。