抗CD33抗體、抗CD33/抗CD3雙特異性抗體及其用途农业专利-农业专业知识服务系统

发明人:: DIEM, MICHAEL,迪姆　麦克,迪姆　麥克,GAUDET, FRANCOIS,高德特　弗朗索瓦,高德特　弗朗索瓦,MCDAID, RONAN,麦克戴德　罗南,麥克戴德　羅南,NAIR-GUPTA, PRIYANKA,尼亚　古普塔　普里扬卡,尼亞　古普塔　普里揚卡

摘要：: Anti-CD33 antibodies and antigen-binding fragments thereof and anti-CD33/anti-CD3 bispecific antibodies or antigen-binding fragments thereof are described. Also described are nucleic acids encoding the antibodies, compositions comprising the antibodies, methods of producing the antibodies, and methods of using the antibodies for treating or preventing diseases, such as cancer.所述者為抗CD33抗體及其抗原結合片段、以及抗CD33/抗CD3雙特異性抗體或其抗原結合片段。亦描述編碼該等抗體之核酸、包含該等抗體之組成物、產生該等抗體之方法、及使用該等抗體治療或預防諸如癌症之疾病的方法。