1. A pharmaceutical composition comprising (i) a compound of formula (I) as an active pharmaceutical ingredient, where R is selected from the group consisting of hydrogen, substituted or unsubstituted alkyl, substituted or unsubstituted cycloalkyl, substituted or unsubstituted alkenyl, substituted or unsubstituted aryl, substituted or unsubstituted arylalkyl , substituted or unsubstituted non-aromatic heterocyclyl, substituted or unsubstituted aromatic heterocyclyl, substituted or unsubstituted heterocyclylalkyl, -COR, -C (O) OR, -C (O) NRR, -CH = NR, -CN, -OR, -OC (O ) R , —S (O) —R, —NRR, —NRC (O) R, —NO, —N = CRR and halogen； R are selected from the group consisting of hydrogen, substituted or unsubstituted alkyl, substituted or unsubstituted cycloalkyl, substituted or unsubstituted alkenyl, substituted or unsubstituted aryl, substituted or unsubstituted arylalkyl, substituted or unsubstituted heterocyclyl, substituted or unsubstituted heterocyclylalkyl, —COR, —C (O) OR, —C (O) NRR, —CH = NR, —CN, —OR, —OC (O) R, -S (O) -R, -NRR, -NRC (O) R, -NO, -N = CRR and halogen； R and R are independently selected from the group consisting of hydrogen, substituted or unsubstituted alkyl, substituted or unsubstituted cycloalkyl replacing unsubstituted or unsubstituted alkenyl, substituted or unsubstituted aryl, substituted or unsubstituted arylalkyl, substituted or unsubstituted heterocyclyl, substituted or unsubstituted heterocyclylalkyl, —COR, —C (O) OR, —C (O) NRR, —CH = NR, —CN, -OR, -OC (O) R, -S (O) -R, -NRR, -NRC (O) R, -NO, -N = CRR and halogen, or together with the phenyl group to which they are attached form a condensed a substituted or unsubstituted aryl group or a fused substituted or unsubstituted heterocyclyl group； R and R are independently selected from the group consisting of hydrogen, substituted or unsubstituted1. Фармацевтическая композиция, содержащая (i) соединение формулы (I) в качестве активного фармацевтического ингредиентагде Rвыбирают из группы, вкл
