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ПРОИЗВОДНЫЕ ТИПА АЗАИНДАЗОЛА ИЛИ ДИАЗАИНДАЗОЛА ДЛЯ ЛЕЧЕНИЯ БОЛИ
专利权人:
ПЬЕР ФАБР МЕДИКАМЕНТ (FR)
发明人:
СОКОЛОФФ Пьер (FR),КАШУ Фредерик (FR)
申请号:
RU2015106434
公开号:
RU2015106434A
申请日:
2013.07.29
申请国别(地区):
RU
年份:
2016
代理人:
摘要:
1. A compound of the following general formula (I): or a pharmaceutically acceptable salt or solvate thereof, a tautomer thereof or a stereoisomer or mixture of stereoisomers in any ratio, such as a mixture of enantiomers, in particular the racemic mixture, Ykazhdy wherein = Y represents independently a group CH or a nitrogen atom, provided that at least one of Y and Ypredstavlyaet a nitrogen atom Ypredstavlyaet a group C-X-Ar, Ypredstavlyaet a CW group, Ar represents an aryl or heteroaryl group optionally substituted by one whether more groups selected from halogen, (C-C) alkyl, (C-C) haloalkyl, (C-C) haloalkoxy, (C-C) galogentioalkoksi, CN, NO, OR, SR, NRR, COR, CONRR , SOR, SONRR, COR, NRCOR, NRSORi RNRR, and / or optionally fused to a heterocycle, X represents a divalent group selected from O, S, S (O), S (O), NR, S (NR), S (O) (NR), S (O) (NR), NRS, NRS (O), NRS (O), CH, CHS, CHS (O), CHS (O), SCH, S (O) CH, S (O) CH, CHCH, CH = CH, C≡C, CHO, OCH, NRCH, and CHNR, W represents a group R, SR, ORili NRR, U represents a group dream NH, one or more hydrogen atoms which may be substituted (C-C) alkyl group, V represents C (O), C (S) or CH , N represents 0 or 1, R represents a hydrogen atom or a group ORili NRR, R is a hydrogen atom, an optionally substituted heterocyclic, NO, ORili NRR, R, R, R-r and R-are each represents independently a hydrogen atom or (C-C) alkyl group, R are each represents independently a hydrogen atom or a (C-C) alkyl, optionally substituted aryl or optionally substituted benzyl group, R, R, r and are each represents independently a hydrogen atom or optionally substituted (C-C) alkyl or (C-C) cycloalkyl group, or optionally substituted heterocycle iRpredstavlyaet is (C-C) alkyl group, for use in treating1. Соединение следующей общей формулы (I):или его фармацевтически приемлемая соль или сольват, его таутомер, либо его стереоизомер или смесь стереоизомеров в любых соотношениях, такая как смесь энантиомеров, в частности рацемическая смесь,гдеY1
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/

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