ТАЧДЖИАН Кэтрин (US),ТАН Сяо-Цин (US),КАРАНЕВСКИ Дональд С. (US),СЕРВАНТ Гай (US),ЛИ Сяодун (US),ЧЖАН Фэн (US),Чэнь Цин (US),ЧЖАН Хун (US),ДЭВИС Тимоти (US),ДАРМОХУСОДО Винсент (US),ВОНГ Мелисса (US)
申请号：
RU2012146608/04
公开号：
RU2012146608A
申请日:
2011.03.31
申请国别(地区):
RU
年份:
2014
代理人:
摘要：
1. A compound having structural Formula (I) or (I '): or, or tautomers, salts and / or solvates, where: A is —OR, —NRC (O) R, —NHOR, —NRR, —NRCOR, -NRC (O) NRR, -NRC (S) NRR or -NRC (= NH) NRR； B is hydrogen, alkyl, substituted alkyl, aryl, substituted aryl, arylalkyl, substituted arylalkyl, acyl, substituted acyl, heteroalkyl, substituted heteroalkyl, heteroaryl substituted with heteroaryl； heteroarylalkyl substituted with heteroarylalkyl； —CN, —OR, —S (O) R, —NRR, —C (O) NRR, —COR, —NRCOR, —NRC (O) NRR, —NRC (S ) NRR, -NRC (= NH) NRR, -SONRR, -NRSOR, -NRSONRR, -B (OR) (OR), -P (O) (OR) (OR) or -P (O) (R) ( OR)； C is -OR, -S (O) R, SOR, -C (O) NRR, -COR, -NRCOR, -NRC (O) N RR, -NRC (= NH) NRR, -SONRR, -NRSOR, -NRSONRR, -B (OR) (OR), -P (O) (OR) (OR), -P (O) (R) (OR ) or heteroaryl； D is aryl, substituted aryl, heteroaryl, substituted heteroaryl, cycloalkyl, substituted cycloalkyl, cycloheteroalkyl or substituted cycloheteroalkyl, where this ring is optionally fused with another aryl, substituted aryl, heteroaryl, substituted cycloalkyl cycloheteroalkyl or substituted cycloheteroalkyl ring； a and b are independently 0, 1 or 2； and R, R, R, R, R, R, R, R and R are independently hydrogen, alkyl, substituted alkyl, aryl, substituted aryl, arylalkyl, substituted arylalkyl, acyl, substituted acyl, heteroalkyl, substituted heteroalkyl, heteroaryl, substituted heteroaryl, heteroaryl or substituted heteroarylalkyl； or alternatively, R and R, R and R, R and R, R and R, R and R or R and R, together with the atoms to which they are bonded, form a cycloheteroalkyl or substituted cycloheteroalkyl ring. 2. The compound according to claim 1, characterized in that the Formula (I) depends on the following conditions: (a)1. Соединение, имеющее структурную Формулу (I) или (I'):или,или таутомеры, соли и/или сольваты, где:А является -OR, -NRC(O)R, -NHOR, -NRR, -NRCOR, -NRC(O)NRR, -NRC(S)NRRили -NRC(=NH)NRR；В является водородом, алкилом, замещенным алкилом, арилом, замещенным арилом, ари
