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PHENOLIC DERIVATIVES AND THEIR PHARMACEUTICAL OR COSMETIC USE
专利权人:
ГАЛДЕРМА РЕСЕРЧ ЭНД ДЕВЕЛОПМЕНТ (FR)
发明人:
ПУАНСАР Седрик (FR),КОЛЛЕТТ Паскаль (FR),МОВЭ Паскаль (FR),ЛЭНЖЕ Жан-Мишель (FR),РЕТОРЕ Сандрин (FR)
申请号:
RU2012131404/04
公开号:
RU2012131404A
申请日:
2010.12.22
申请国别(地区):
RU
年份:
2014
代理人:
摘要:
1. The compounds of formula (I): in which: - R represents a group C-alkyl, C-cycloalkyl, C-alkyloxy, -S (O) -C-alkyl, C-fluoroalkyl, C-fluoroalkyloxy, - (CH) -C -cycloalkyl, C-alkyl-OH, - (CH) -C-alkyloxy, - (CH) -C-fluoroalkyl, - (CH) -O-C-fluoroalkyl, COR, CN, NO, NRR, halogen or phenyl or a heteroaryl group containing either a) from 1 to 4 nitrogen atoms, or b) an oxygen or sulfur atom and 1 or 2 nitrogen atoms; these phenyl and heteroaryl groups may possibly be substituted with one, two or three R groups, the same or different; - R represents a C-alkyl, C-cycloalkyl, C-alkyloxy, -S (O) -C-alkyl, C- group fluoroalkyl, C-fluoroalkyloxy, - (CH) -C-cycloalkyl, C-alkyl-OH, - (CH) -C-alkyloxy, - (CH) -C-fluoroalkyl, - (CH) -O-C-fluoroalkyl, COR, CN, NO, NRR, hydrogen, halogen or a phenyl or heteroaryl group containing either a) from 1 to 4 nitrogen atoms, or b) an oxygen or sulfur atom and 1 or 2 nitrogen atoms; these phenyl and heteroaryl groups may possibly be substituted by one, two or three R groups, identical or different; - R and R, identical or different, represent a hydrogen atom or a group C-alkyl, C-cycloalkyl, C-fluoroalkyl, - ( CH) -C-cycloalkyl, C-alkyl-OH, - (CH) -C-alkyloxy, - (CH) -C-cycloalkyl, - (CH) -C-fluoroalkyl or - (CH) -O-C-fluoroalkyl ; optionally, the R and R groups can form, with the carbon atom that carries them, a C-cycloalkyl group or a heterocycle such as tetrahydrofuran, tetrahydropyran, tetrahydrothiopyran, tetrahydro-1-hydroxythiopyran or tetrahydro-1,1-dioxithiopyrano; R, R, R, R, identical or different, are either a hydrogen atom or a C-alkyl, C-cycloalkyl, C-alkyloxy, -S (O) -C-alkyl group, C-fluoroalkyl, C-fluoroalkyloxy, - (CH) -C-cycloalkyl, C-alkyl-OH, - (CH) -C-alkyloxy, - (CH) -C-fluoroalkyl, - (CH) -O-C- fluoroalkyl, COR, CN, NRR or halogen, or fe1. Соединения формулы (I):в которой:- Rобозначает группу С-алкил, С-циклоалкил, С-алкилокси, -S(O)-С-алкил, С-фторалкил, С-фторалкилокси, -(CH)-С-циклоалкил, С-алкил-ОН, -(CH)-С-алк
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/
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