CASARA, Patrick,LE DIGUARHER, Thierry,HENLIN, Jean-Michel,STARCK, Jérôme-Benoît,LE TIRAN, Arnaud,DE NANTEUIL, Guillaume,GENESTE, Olivier,DAVIDSON, James Edward Paul,MURRAY, James Brooke,CHEN, I-Jen,WA
申请号：
ES14758604
公开号：
ES2687475T3
申请日:
2014.07.22
申请国别(地区):
ES
年份:
2018
代理人:
摘要：
Compound of formula (I): ** Formula ** in which: - W represents a CH group while A1 and A2 respectively represent a hydrogen atom and a methyl group, or W represents a CH group while A1 and A2 they form with the carbon atoms carried by a cliclohexenyl or a benzo cycle optionally substituted by a halogen atom, - T represents a hydrogen atom, a linear or branched (C1-C6) alkyl optionally substituted by one to three halogen atoms , a (C1-C4) -NR1 R2 alkyl group or a (C1-C4) alkyl-OR6-R1 and R2 group independently represent each other a hydrogen atom or a linear or branched (C1-C6) alkyl group, or R1 and R2 form a heterocycloalkyl with the nitrogen atom, - R3 represents an aryl or heteroaryl group, it being understood that one or more carbon atoms of the above groups, or of their eventual substituents, may or may be deuterated (s) - R4 represents a group aryl or heteroaryl, it being understood that one or more carbon atoms of the above groups, or of their eventual substituents, may or may be deuterated (s) - R5 represents a hydrogen or halogen atom, a (C1-C6) alkyl group linear or branched or a linear or branched (C1-C6) alkoxy group, - R6 represents a hydrogen atom or a linear or branched (C1-C6) alkyl group, - Ra, Rb, Rc and Rd independently represent one of the other R7, a halogen atom, a linear or branched (C1-C6) alkoxy group, a hydroxy group, a linear or branched (C1-C6) polyhalogenoalkyl group, a trifluoromethoxy group, -NR7R7 `, nitro, or the substituents of one of the pairs (Ra, Rb), (Rb, Rc) or (Rc and Rd) together with the carbon atoms that carry them a cycle consisting of 5 to 7 links, which may contain one to two heteroatoms chosen between oxygen and sulfur, it being also understood that one or more carbon atoms of c The previously defined icon may or may be deuterated (s) or substituted by one to 3 groups selected from halogen or linear or branched (C1-C6) alkyl or else Ra and Rd each represent a hydrogen atom, Rb represents a hydrogen, a halogen, a hydrox
