KRISTALNE OBLIKE 4-((2,4-DIKLORO-5-METOKSIFENIL)AMINO)-6-METOKSI-7-(3- (4-METIL-1-PIPERAZINIL)PROPOKSI)-3-KINOLINKARBONITRIL IN METODE ZA PRIPRAVO LE-TEH

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专利权人:

WYETH LLC

发明人:

TESCONI MARC SADLER,FEIGELSON GREGG,STRONG HENRY,WEN HONG,TESCONI Marc Sadler,FEIGELSON Gregg,STRONG Henry,WEN Hong

申请号：

SI200631732

公开号：

SI1902029T1

申请日:

2006.06.28

申请国别(地区):

SI

年份:

2014

代理人:

摘要：

This invention is directed to a crystalline 4-[(2,4-dichloro-5-methoxyphenyl)amino]-6-methoxy-7-[3-(4-methyl-1-piperazinyl)propoxy]-3-quinolinecarbonitrile monohydrate having an x-ray diffraction pattern wherein 2&thetas； angles (°) of significant peaks are at about: 9.19, 11.48, 14.32, 19.16, 19.45, 20.46, 21.29, 22.33, 23.96, 24.95, 25.29, 25.84, 26.55, 27.61, and 29.51, and a transition temperature of about 109° C. to about 115° C.

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