Crystalline forms of 4 - [(2,4-dichloro-5-methoxyphenyl) amino] -6-methoxy-7- [3- (4-methyl-1-piperazinyl) propoxy] -3-quinolinecarbonitrile and methods of preparing the same
TESCONI, MARC,FEIGELSON, GREGG,STRONG, HENRY,WEN, HONG
申请号：
ES06774184
公开号：
ES2449197T3
申请日:
2006.06.28
申请国别(地区):
ES
年份:
2014
代理人:
摘要：
An isolated crystalline Form I of 4 - [(2,4-dichloro-5-methoxyphenyl) amino] -6-methoxy-7- [3- (4-methyl-1-piperazinyl) propoxy] -3-quinolinecarbonitrile monohydrate having an X-ray diffraction pattern, in which all 2θ (°) angles of significant peaks are at approximately: 9.19, 11.48, 14.32, 22.33 and 25.84.Una Forma I cristalina aislada de 4-[(2,4-dicloro-5-metoxifenil)amino]-6-metoxi-7-[3-(4-metil-1-piperazinil)propoxi]-3-quinolincarbonitrilo monohidrato que tiene un patrón de difracción de rayos X, en el que todos losángulos 2&theta； (°) de picos significativos están en aproximadamente: 9,19, 11,48, 14,32, 22,33 y 25,84.
