2. Cart19 was used to consume normal B cells to induce tolerance

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专利权人:

ДЗЕ ТРАСТИЗ ОФ ДЗЕ ЮНИВЕРСИТИ ОФ ПЕНСИЛЬВАНИЯ

发明人:

Левин, Брюс Л.,Кейлос, Майкл Д.,Джун, Карл Х.

申请号：

EA201992742

公开号：

EA201992742A2

申请日:

2013.07.12

申请国别(地区):

EA

年份:

2020

代理人:

摘要：

The present invention provides compositions and methods for inducing tolerance in a human. The invention includes administering a genetically modified T cell expressing a CAR wherein the CAR comprises an antigen binding domain, a transmembrane domain, a costimulatory signaling region, and a CD3 zeta signaling domain.

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/