USE OF CART19 TO DEPLETE NORMAL B CELLS TO INDUCE TOLERANCE

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专利权人:

The Trustees of the University of Pennsylvania

发明人:

June, Carl H.,Levine, Bruce L.,Kalos, Michael D.

申请号：

AU2018203756

公开号：

AU2018203756A1

申请日:

2018.05.29

申请国别(地区):

AU

年份:

2018

代理人:

摘要：

#$%^&*AU2018203756A120180621.pdf#####ABSTRACT Compositions and methods for inducing tolerance and depleting B cells in a human are provided. This includes administering a genetically modified T cell expressing a CAR, wherein the CAR comprises an antigen binding domain, a transmembrane domain, a costimulatory signalling region and a CD3 zeta signalling domain.

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/