USE OF CART19 TO DEPLETE NORMAL B CELLS TO INDUCE TOLERANCE

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专利权人:

The Trustees of the University of Pennsylvania

发明人:

Levine, Bruce L.,Kalos, Michael D.,June, Carl H.

申请号：

AU2020200315

公开号：

AU2020200315A1

申请日:

2020.01.16

申请国别(地区):

AU

年份:

2020

代理人:

摘要：

#$%^&*AU2020200315A120200206.pdf#####ABSTRACT The present invention provides compositions and methods for inducing tolerance in a human. The invention includes administering a genetically modified T cell expressing a CAR wherein the CAR comprises an antigen binding domain, a transmembrane domain, a costimulatory signalling region, and a CD3 zeta signalling domain.WO 2014/012001 PCT/US2013/050293 1/16 V4p zS CL/ /L /L SU SL SL /CC <；/

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/