HUNTER, Alan A,LINKE, Thomas T,PABST, Tim T,WENDELER, Michaela M,WANG, Xiangyang,THOMPSON, Chris C,XI, Guoling G,FULTON, Andrew A,‧亨德,‧林克,‧派斯特,‧溫得勒,王向陽,‧湯普森,‧習,‧弗爾頓
申请号：
HK16103571.3
公开号：
HK1215547A
申请日:
2016.03.29
申请国别(地区):
HK
年份:
2016
代理人:
摘要：
The present invention provides methods of preparing active immunoconjugates, including anti-CD22 immunoconjugates. Suitably, the methods include a fed-batch refolding process and/or column stripping process that result in an increase in yield of the immunoconjugate over other processes that do not utilize the methods.
