HUNTER, Alan,LINKE, Thomas,PABST, Tim,WENDELER, Michaela,WANG, Xiangyang,XI, Guoling,FULTON, Andrew,THOMPSON, Chris
申请号：
DK13863999
公开号：
DK2934597T3
申请日:
2013.12.19
申请国别(地区):
DK
年份:
2019
代理人:
摘要：
The present invention provides methods of preparing active immunoconjugates, including anti-CD22 immunoconjugates. Suitably, the methods include a fed-batch refolding process and/or column stripping process that result in an increase in yield of the immunoconjugate over other processes that do not utilize the methods.
