HUNTER, ALAN,LINKE, THOMAS,PABST, TIM,WENDELER, MICHAELA,WANG, XIANGYANG,THOMPSON, CHRIS,XI, GUOLING,FULTON, ANDREW
申请号：
CA2894908
公开号：
CA2894908A1
申请日:
2013.12.19
申请国别(地区):
CA
年份:
2014
代理人:
摘要：
The present invention provides methods of preparing active immunoconjugates, including anti-CD22 immunoconjugates. Suitably, the methods include a fed-batch refolding process and/or column stripping process that result in an increase in yield of the immunoconjugate over other processes that do not utilize the methods.
