HUNTER, Alan,LINKE, Thomas,PABST, Tim,WENDELER, Michaela,WANG, Xiangyang,TOHMPSON, Chris,XI, Guoling,FULTON, Andrew
申请号:
HK16104008.4
公开号:
HK1216142A
申请日:
2016.04.08
申请国别(地区):
HK
年份:
2016
代理人:
摘要:
The present invention provides methods of preparing active immunoconjugates, including anti-CD22 immunoconjugates. Suitably, the methods include a fed-batch refolding process and/or column stripping process that result in an increase in yield of the immunoconjugate over other processes that do not utilize the methods.