PURPOSE: A composition containing Viscum album extract is provided to enhance exercise ability and suppress fatigue in muscle. CONSTITUTION: A Viscum album extract which relieves fatigue is obtained by cold water extraction or hot water extraction. The cold water extract is obtained by adding 1L of water to 200g of Viscum album then stirring at 4°;C for two hours. The hot water extract is obtained by adding 1L of water to 200g of residual extract of cold water then heating at 100°;C for 30 minutes. A functional food composition or pharmaceutical composition for enhancing exercise activity or relieving fatigue contains the Viscum album extract as an active ingredient.본 발명은 운동수행능력 증강 및 피로억제 효과를 갖는 겨우살이(Mistletoe; Viscum album) 추출물에 관한 것으로, 본 발명 겨우살이 추출물 또는 이를 함유하는 기능성 식품 또는 약제학적 조성물은 운동수행능력을 증강시키고 근육 내의 피로를 억제하는 효과가 있어 체력 및 운동능력 증진에 뛰어난 효과를 나타내는 바, 기능성 식품 또는 의약 분야에서 매우 유용한 발명이다.