SCHRYVERS ANTHONY B,MORAES TREVOR F,GRAY-OWEN SCOTT
申请号：
IN201627017595
公开号：
IN201627017595A
申请日:
2016.05.23
申请国别(地区):
IN
年份:
2016
代理人:
摘要：
The disclosure provides immunogenic compositions comprising a polypeptide comprising a C lobe domain or an N lobe domain of a HIBP surface receptor protein obtainable from or obtained from a Gram negative bacterial species. The HIBP surface receptor proteins have been modified in such a manner that they are unable to bind host iron binding protein. Methods of making and using these immunogenic positions to prepare animal and human vaccines are also provided.
