ALEXANDER HEGMANS,BRUCE W. FENSKE,DAN J. TREPANIER,MARK D. ABEL,SHIN SUGIYAMA,DAREN R. URE
申请号：
MYPI 2013002159
公开号：
MY165152A
申请日:
2011.12.14
申请国别(地区):
MY
年份:
2018
代理人:
摘要：
ANALOGUES OF CYCLOSPORINE-A ARE DISCLOSED COMPRISING MODIFICATIONS OF THE SUBSTITUENTS AS THE POSITIONS OF AMINO ACIDS 1 AND 3, ACCORDING TO THE FOLLOWING FORMULA. THE DISCLOSED COMPOUNDS INCLUDE COMPOUNDS HAVING AFFINITY FOR CYCLOPHILIN, INCLUDING CYCLOPHILIN-A, AND REDUCED MUNOSUPPRESSIVITY IN COMPARISON WITH CYCLOSPORIN-A AND ANALOGS THEREOF MODIFIED SOLELY AT POSITION 1.
