Hegmans, Alexander,Fenske, Bruce W.,Trepanier, Dan J.,Abel, Mark D.,Sugiyama, Shin,Ure, Daren R.
申请号：
AU2011342284
公开号：
AU2011342284C1
申请日:
2011.12.14
申请国别(地区):
AU
年份:
2017
代理人:
摘要：
Analogues of cyclosporin-A are disclosed comprising modifications of the substituents as the positions of amino acids 1 and 3, according to the following Formula (I). The disclosed compounds include compounds having affinity for cyclophilin, including cyclophilin-A, and reduced immunosuppressivity in comparison with cyclosporin-A and analogs thereof modified solely at position 1.
