ГАЛЛАХЕР Михела (US),ХАБЕРМАН Ребекка (US),КОХ Мин Тен (US)
申请号：
RU2013141155/15
公开号：
RU2013141155A
申请日:
2012.02.09
申请国别(地区):
RU
年份:
2015
代理人:
摘要：
1. A method of treating a central nervous system (CNS) disorder that is accompanied by cognitive impairment in a subject in need of such treatment or is at risk of such a disorder, a method of delaying or slowing the progression of a cognitive impairment, or a method of reducing the rate of cognitive decline in a subject, wherein the method comprises the step of administering to the subject a therapeutically effective amount of a synaptic vesicle 2A protein inhibitor (SV2A) or a pharmaceutical thereof tsevticheski acceptable salt, hydrate, solvate or polymorph modifikatsii.2. The method according to claim 1, wherein the SV2A inhibitor or a pharmaceutically acceptable salt, hydrate, solvate or polymorphic modification thereof is selected from the group consisting of levetiracetam, celethracetam and brivaracetam or their pharmaceutically acceptable salts, hydrates, solvates and polymorphic modifications. The method of claim 2, wherein the SV2A inhibitor or a pharmaceutically acceptable salt, hydrate, solvate or polymorphic modification thereof is levetiracetam or a pharmaceutically acceptable salt, hydrate, solvate or polymorphic modification thereof. The method of claim 2, wherein the SV2A inhibitor or a pharmaceutically acceptable salt, hydrate, solvate or polymorphic modification thereof is brivaracetam or a pharmaceutically acceptable salt, hydrate, solvate or polymorphic modification thereof. The method according to claim 2, wherein the SV2A inhibitor or a pharmaceutically acceptable salt, hydrate, solvate or polymorphic modification thereof is seletracetam or a pharmaceutically acceptable salt, hydrate, solvate or polymorphic modification thereof. Method according to any1. Способ лечения расстройства центральной нервной системы (ЦНС), которое сопровождается когнитивными нарушениями, у субъекта, нуждающегося в подобном лечении или находящегося в группе риска возникновения подобного расстройства, способ задержки или замедления прогрессирования когнитивного нарушен
