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METHODS AND COMPOSITIONS FOR THE SUPPLY OF ARYL SULPHATASE A
专利权人:
Inc.;Shire Human Genetic Therapies
发明人:
SALAMAT-MILLER, Nazila,TAYLOR, Katherine,CAMPOLIETO, Paul,SHAHROKH, Zahra,PAN, Jing,CHARNAS, Lawrence,WRIGHT, Teresa Leah,CALIAS, Pericles
申请号:
DK11799037
公开号:
DK2585104T3
申请日:
2011.06.25
申请国别(地区):
DK
年份:
2019
代理人:
摘要:
The present invention provides, among other things, compositions and methods for CNS delivery of lysosomal enzymes for effective treatment of lysosomal storage diseases. In some embodiments, the present invention includes a stable formulation for direct CNS intrathecal administration comprising an arylsulfatase A (ASA) protein, salt, and a polysorbate surfactant for the treatment of Metachromatic Leukodystrophy Disease.
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/

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