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Pyridine pyrazolo derivatives as NADPH oxidase inhibitors
- 专利权人:
- GenKyoTex SA
- 发明人:
- PAGE, Patrick,ORCHARD, Mike,LALEU, Benoît,GAGGINI, Francesca
- 申请号：
- ES09815761
- 公开号：
- ES2561210T3
- 申请日:
- 2009.09.22
- 申请国别(地区):
- ES
- 年份:
- 2016
- 代理人:
- 摘要：
- A pyrazine pyridine derivative according to Formula (I): ** Formula ** wherein G1 is selected from H； optionally substituted acyl； optionally substituted C1-C6 alkyl, optionally substituted C3-C8-alkyl alkyl, optionally substituted heterocycloalkyl, optionally substituted aryl alkyl, and optionally substituted heteroaryl alkyl； G2 is selected from - CHR1R2 and an optionally substituted saturated ring system selected from optionally substituted C3-C8-cycloalkyl and optionally substituted heterocycloalkyl； R1 and R2 are selected, independently of H； optionally substituted alkoxy； optionally substituted C1-C6 alkoxy； optionally substituted amino； optionally substituted amino alkyl； optionally substituted acyl； C1-C6 alkyl optionally substituted； C2-C6 optionally substituted alkenyl； C2-C6 optionally substituted alkynyl； optionally substituted aryl； C1-C6 alkyl aryl optionally substituted； aryl C1-C6 alkyl optionally substituted； optionally substituted heteroaryl； C1-C6 optionally substituted alkyl heteroaryl； optionally substituted C1-C6 alkyl heteroaryl； C2-C6 optionally substituted alkenyl aryl； C2-C6 alkenyl optionally substituted alkenyl； C2-C6 optionally substituted alkenyl heteroaryl； optionally substituted C2-C6 heteroaryl； C3-C8-cycloalkyl optionally substituted； optionally substituted heterocycloalkyl； C1-C6 alkyl C3-C8-cycloalkyl optionally substituted； C3-C8-C1-C6 cycloalkyl optionally substituted alkyl； C1-C6 optionally substituted heterocycloalkyl and optionally substituted heterocycloalkyl C1-C6 alkyl； or - CHR1R2 together forming an optionally substituted ring selected from optionally substituted C3-C8-cycloalkyl and optionally substituted heterocycloalkyl； G3 is selected from H； optionally substituted amino； optionally substituted aminoalkyl； optionally substituted aminocarbonyl； optionally substituted alkoxy； optionally substituted C1-C6 alkoxy； optionally substituted acyl； C1-C6 alkyl optionally substituted； C2-C6 optionally substituted alkenyl； C2-C6
- 来源网站：
- 中国工程科技知识中心
- 来源网址：
- http://www.ckcest.cn/home/
