Pyrazine pyridine derivatives as NADPH inhibitors

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专利权人:

GENKYOTEX SA

发明人:

PAGE, PATRICK,ORCHARD, MIKE,LALEU, BENOÎT,GAGGINI, FRANCESCA

申请号：

ES09787271

公开号：

ES2528096T3

申请日:

2009.09.22

申请国别(地区):

ES

年份:

2015

代理人:

摘要：

A pyrazine pyridine derivative according to Formula (I): ** Formula ** wherein G1 of H is selected； optionally substituted acyl； optionally substituted C1-C6 alkyl acyl； optionally substituted C3-C8 alkyl-cycloalkyl alkyl； optionally substituted heterocycloalkyl alkyl； optionally substituted aryl alkyl； and optionally substituted heteroaryl alkyl； G2 is selected from H； optionally substituted C1-C6 alkyl； optionally substituted C2-C6 alkenyl； optionally substituted C2-C6 alkynyl； optionally substituted aryl； optionally substituted optionally substituted C1-C6 alkyl aryl； optionally substituted aryl C1-C6 alkyl； optionally substituted heteroaryl； optionally substituted alkyl heteroaryl； optionally substituted C1-C6 alkyl heteroaryl； optionally substituted C2-C6 alkenyl aryl； optionally substituted aryl C2-C6 alkenyl； optionally substituted C2-C6 alkenyl heteroaryl； optionally substituted C2-C6 alkenyl heteroaryl； optionally substituted C3-C8-cycloalkyl； optionally substituted heterocycloalkyl； optionally substituted C3-C8-cycloalkyl alkyl； optionally substituted C3-C8-C1-C6 cycloalkyl alkyl； optionally substituted C1-C6 alkyl heterocycloalkyl and optionally substituted heterocycloalkyl C1-C6 alkyl； G3 is selected from H； optionally substituted amino； optionally substituted aminoalkyl； optionally substituted aminocarbonyl； optionally substituted alkoxy； optionally substituted C1-C6 alkoxy alkyl； optionally substituted carbonyl； optionally substituted C1-C6 alkyl； optionally substituted C2-C6 alkenyl； optionally substituted C2-C6 alkynyl； optionally substituted aryl； optionally substituted aryl C1-C6 alkyl； optionally substituted heteroaryl； optionally substituted C1-C6 alkyl heteroaryl； optionally substituted C1-C6 alkyl heteroaryl； optionally substituted C2-C6 alkenyl aryl； optionally substituted aryl C2-C6 alkenyl； optionally substituted C2-C6 alkenyl heteroaryl； optionally substituted C2-C6 alkenyl heteroaryl； optionally substituted C3-C8-cycloalkyl； optionally sub

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