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Pyrazol pyridine derivatives as NADPH oxidase inhibitors
- 专利权人:
- GenKyoTex SA
- 发明人:
- Page, Patrick,Orchard, Mike,Laleu, Benoît,Gaggini, Francesca
- 申请号：
- ES13177370
- 公开号：
- ES2560840T3
- 申请日:
- 2009.09.22
- 申请国别(地区):
- ES
- 年份:
- 2016
- 代理人:
- 摘要：
- A pyrazolo pyridine derivative according to Formula (I): ** Formula ** where G1 is H； G2 is selected from optionally substituted aryl and optionally substituted heteroaryl； G3 is selected from - (CH2) n-R1 and - (CH2) p-R5； R1 is selected from -NR2R3； -OR4； optionally substituted heterocycloalkyl； optionally substituted heteroaryl； -CHR6R7； optionally substituted acyl and -C (O) NR2R3； R2 and R3 are independently selected from H； C1-C6 optionally substituted alkyl； C2-C6 optionally substituted alkenyl； C2-C6 optionally substituted alkynyl； optionally substituted aryl； C1-C6 optionally substituted alkyl aryl； C1-C6 aryl optionally substituted alkyl； optionally substituted heteroaryl； optionally substituted alkyl heteroaryl； optionally substituted C1-C6 heteroaryl alkyl； Optionally substituted C2-C6 alkenyl aryl； optionally substituted C2-C6 aryl alkenyl； Optionally substituted C2-C6 alkenyl heteroaryl； optionally substituted C2-C6 heteroaryl alkenyl； Optionally substituted C3-C8-cycloalkyl； optionally substituted heterocycloalkyl； optionally substituted C3-C8-cycloalkyl alkyl； C3-C8-C1-C6 cycloalkyl optionally substituted alkyl； Optionally substituted C1-C6 alkyl heterocycloalkyl and optionally substituted heterocycloalkyl C1-C6 alkyl or NR2R3 forming a ring selected from optionally substituted heteroaryl and optionally substituted heterocycloalkyl； R4 is selected from H； optionally substituted C1-C6 alkoxy； C1-C6 optionally substituted alkyl； C2-C6 optionally substituted alkenyl； C2-C6 optionally substituted alkynyl； optionally substituted aryl； C1-C6 optionally substituted alkyl aryl； C1-C6 aryl optionally substituted alkyl； optionally substituted heteroaryl； optionally substituted alkyl heteroaryl； optionally substituted C1-C6 heteroaryl alkyl； Optionally substituted C2-C6 alkenyl aryl； optionally substituted C2-C6 aryl alkenyl； Optionally substituted C2-C6 alkenyl heteroaryl； optionally substituted C2-C6 heteroaryl alkenyl； Optionally substituted C3-C8-cycloalkyl
- 来源网站：
- 中国工程科技知识中心
- 来源网址：
- http://www.ckcest.cn/home/
