Use of a steroid sulfatase inhibitor, as well as pharmaceutically acceptable salts thereof, for the preparation of a pharmaceutical composition for the treatment or prophylaxis of a disease or condition associated with premature uterine contractions, wherein the steroid inhibitor Sulfatase is a sulfamate of Formula (I): ** Formula ** in which R1 and R2 are independently selected from H, optionally substituted C1-C6 alkyl, optionally substituted C2-C6 alkenyl, optionally substituted C2-C6 alkynyl, alkoxy, optionally substituted C3-C8 cycloalkyl, optionally substituted heterocycloalkyl, optionally substituted acyl, aryl, heteroaryl, optionally substituted alkyl (C1-C6) aryl, optionally substituted (C1-C6) alkyl, optionally substituted C1-C6 alkyl, C3-C8 alkyl substituted, optionally substituted (C1-C6) alkyl heterocycloalkyl, optionally substituted aryl-C1-C6 alkyl, heteroaryl-C1-C6 alkyl or optionally substituted, optionally substituted cycloalkyl (C3-C8) C1-C6 alkyl and optionally substituted heterocycloalkyl-C1-C6 alkyl or R1 and R2 together form an optionally substituted alkenyl group； R3 is a group selected from a group of Formulas (II '), (II' '), (III') and (IV '): ** Formula ** in which R4 and R5 are independently selected from H； halogen； nitro； optionally substituted amino； optionally substituted sulfanyl； optionally substituted acyl； optionally substituted thioalkyl； optionally substituted C1-C6 alkyl； optionally substituted C2-C6 alkenyl； optionally substituted alkoxy； optionally substituted alkoxy-alkyl； optionally substituted amino-alkyl； optionally substituted C3-C8 cycloalkyl； and optionally substituted aryl； R6, R7, R8, R9, R10, R11, R12, R13 and R14 are independently selected from H； OH； halogen and optionally substituted C1-C6 alkyl； R15 is selected from H； OH； halogen； optionally substituted sulfamate and C1-C6 alkyl； R16, R17 and R18 are independently selected from H； OH； halogen； optionally substituted C1-C6 alkyl； optionally substituted C2-C6 al
