STEENECK, CHRISTOPH,GEGE, CHRISTIAN,KINZEL, OLAF,KLEYMANN, GERALD,HOFFMANN, THOMAS,GOLDBERG, STEVEN,FOURIE, ANNE M.,XUE, XIAOHUA
申请号：
CA2965515
公开号：
CA2965515A1
申请日:
2015.10.30
申请国别(地区):
CA
年份:
2016
代理人:
摘要：
The present invention comprises compounds of Formula I. Formula I wherein: R1, R2, R3, R4, R5, R7, R8, and (A) are defined in the specification. The invention also comprises a compound of Formula I for use in a method of treating or ameliorating a syndrome, disorder or disease, wherein said syndrome, disorder or disease is rheumatoid arthritis or psoriasis. The invention also comprises a compound for use in a method of modulating ROR?t activity in a mammal by administration of a therapeutically effective amount of at least one compound of claim 1.
