MCCLURE, Kelly,TANIS, Virginia M.,FENNEMA, Elizabeth G.,LEBSACK, Alec D.,MARTIN, Connor L.,VENKATESAN, Hariharan,XUE, Xiaohua,WOODS, Craig R.,GOLDBERG, Steven
申请号：
PH12018502209
公开号：
PH12018502209A1
申请日:
2018.10.16
申请国别(地区):
PH
年份:
2019
代理人:
摘要：
The present invention comprises compounds of Formula (I) wherein: A1, A2, A3, A4, A5, R1, and R2 are defined in the specification. The invention also comprises a method of treating or ameliorating a syndrome, disorder or disease, wherein the syndrome, disorder or disease is rheumatoid arthritis or psoriasis. The invention also comprises a method of modulating ROR?t activity in a mammal by administration of a therapeutically effective amount of at least one compound of Formula I.
