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HETEROARYL LINKED QUINOLINYL MODULATORS OF RORyt
专利权人:
Janssen Pharmaceutica NV
发明人:
Kristi A. Leonard,Kent Barbay,James P. Edwards,Kevin D. Kreutter,David A. Kummer,Umar Maharoof,Rachel Nishimura,Maud Urbanski,Hariharan Venkatesan,Aihua Wang,Ronald L. Wolin,Craig R. Woods,Anne Fourie
申请号:
US14053707
公开号:
US20140107097A1
申请日:
2013.10.15
申请国别(地区):
US
年份:
2014
代理人:
摘要:
The present invention comprises compounds of Formula I.wherein:R1, R2, R3, R4, R5, R6, R7, R8, and R9 are defined in the specification.The invention also comprises a method of treating or ameliorating a syndrome, disorder or disease, wherein said syndrome, disorder or disease is rheumatoid arthritis or psoriasis. The invention also comprises a method of modulating RORγt activity in a mammal by administration of a therapeutically effective amount of at least one compound of claim 1.
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