KRISTI A. LEONARD,KENT BARBAY,JAMES P. EDWARDS,KEVIN D. KREUTTER,DAVID A. KUMMER,UMAR MAHAROOF,RACHEL NISHIMURA,MAUD URBANSKI,HARIHARAN VENKATESAN,AIHUA WANG,RONALD L. WOLIN,CRAIG R. WOODS,ANNE FOURIE
申请号:
US14513426
公开号:
US20150111870A1
申请日:
2014.10.14
申请国别(地区):
US
年份:
2015
代理人:
摘要:
The present invention comprises compounds of Formula I.wherein:R1, R2, R3, R4, R5, R6, R7, R8, and R9 are defined in the specification.The invention also comprises a method of treating or ameliorating a syndrome, disorder or disease, wherein said syndrome, disorder or disease is rheumatoid arthritis or psoriasis. The invention also comprises a method of modulating RORγt activity in a mammal by administration of a therapeutically effective amount of at least one compound of claim 1.