MODULATEURS QUINOLINYL À LIAISON ALKYLE DE ROR(GAMMA)T

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专利权人:

Janssen Pharmaceutica NV

发明人:

申请号：

EP14853874.7

公开号：

EP3057421A4

申请日:

2014.10.14

申请国别(地区):

EP

年份:

2017

代理人:

摘要：

The present invention comprises compounds of Formula I. wherein: R1, R2, R3, R4, R5, R6, R7, R8, and R9 are defined in the specification. The invention also comprises a method of treating or ameliorating a syndrome, disorder or disease, wherein said syndrome, disorder or disease is rheumatoid arthritis or psoriasis. The invention also comprises a method of modulating ROR&gamma；t activity in a mammal by administration of a therapeutically effective amount of at least one compound of claim 1.

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