GOLDBERG, STEVEN,MCCLURE, KELLY,TANIS, VIRGINIA M.,FENNEMA, ELIZABETH G.,LEBSACK, ALEC D.,MARTIN, CONNOR L.,VENKATESAN, HARIHARAN,XUE, XIAOHUA,WOODS, CRAIG R.
申请号：
CA3022318
公开号：
CA3022318A1
申请日:
2017.04.26
申请国别(地区):
CA
年份:
2017
代理人:
摘要：
The present invention comprises compounds of Formula (I) wherein: A1, A2, A3, A4, A5, R1, and R2 are defined in the specification. The invention also comprises a method of treating or ameliorating a syndrome, disorder or disease, wherein the syndrome, disorder or disease is rheumatoid arthritis or psoriasis. The invention also comprises a method of modulating ROR?t activity in a mammal by administration of a therapeutically effective amount of at least one compound of Formula I.
