Steven Goldberg,Christoph Steeneck,Christian Gege,Olaf Kinzel,Gerald Kleymann,Thomas Hoffmann,Anne M. Fourie,Xiaohua Xue
申请号：
US15812528
公开号：
US20180064690A1
申请日:
2017.11.14
申请国别(地区):
US
年份:
2018
代理人:
摘要：
The present invention comprises compounds of Formula Iwherein:R1, R2, R3, R4, R5, R7, R8, andare defined in the specification.The invention also comprises a method of treating or ameliorating a syndrome, disorder or disease, wherein the syndrome, disorder or disease is rheumatoid arthritis or psoriasis. The invention also comprises a method of modulating RORγt activity in a mammal by administration of a therapeutically effective amount of at least one compound of Formula I.
