Extract of Java silicate, extraction method and use thereof as proton pump down regulator, enzyme inhibitor and mucosal protective agent农业专利-农业专业知识服务系统

发明人:: アリフィン，ポッピー・フィルザニ,エル．ウェー．，ディージー・ディア・ドウィ,ユリアニ，ヴェロニカ,シナンベラ，ジェームズ・エム,チャンドラウィナタ，レイモンド・エル,アリフィン,ポッピー・フィルザニ,エル.ウェー.,ディージー・ディア・ドウィ,ユリアニ,ヴェロニカ,シナンベラ,ジェームズ・エム,チャンドラウィナタ,レイモンド・エル

摘要：: Extract and/or fraction from Cinnamomum burmanii (DLBS2411) related to its extraction method and its biological activities show activities as antiulcer by conferring mucoprotection and down-regulating H+/K+ ATPase. Treatment with DLBS2411 decreases the H+/K+ ATPase mRNA level in HEK 293 and gastric parietal cells. In addition, DLBS2411 inhibits activity of H+/K+ ATPase gastric enzyme wherein pH influences this inhibition mechanism. DLBS2411 also has characteristic as antioxidant which is shown by the increase of reducing power as the given dosage increases.