Deasy Diah Dwi R.W.;James M. Sinambela;Poppy Firzani Arifin;Raymond R. Tjandrawinata;Veronika Yuliani
发明人:
Poppy Firzani Arifin,Deasy Diah Dwi R.W.,Veronika Yuliani,James M. Sinambela,Raymond R. Tjandrawinata
申请号:
US14003732
公开号:
US20140079820A1
申请日:
2012.03.09
申请国别(地区):
US
年份:
2014
代理人:
摘要:
Extract and/or fraction from Cinnamomum burmanii (DLBS2411) related to its extraction method and its biological activities show activities as antiulcer by conferring mucoprotection and down-regulating H+/K+ ATPase. Treatment with DLBS2411 decreases the H+/K+ ATPase mRNA level in HEK 293 and gastric parietal cells. In addition, DLBS2411 inhibits activity of H+/K+ ATPase gastric enzyme wherein pH influences this inhibition mechanism. DLBS2411 also has characteristic as antioxidant which is shown by the increase of reducing power as the given dosage increases.